Publications

You want to publish data acquired with support of the Microscopy Core Facility?

Please, consider the following information regarding “Authorships” and “Acknowledgements”:

Authorships:

The core facility personnel may have contributed significantly to your research project (e.g. conception of experimental design, full sample preparation and service imaging, experimental optimization, scientific and technical project discussions, etc.). Authorship may also be appropriate according to good scientific practice. Payment for our services does not argue against an authorship, as the finacial charge can be consider for the temporary employment of personell and the purchase of consumables. Both would also apply for internal group members. More information can be found at https://btc.uni-bonn.de/dfg/ and at https://wissenschaftliche-integritaet.de/en/code-of-conduct/authorship/.

Acknowledgements:

The DFG requires you to mention any use of the Core Facility as an acknowledgment in publications. In accordance with the DFG recommendations we ask you to use the following phrase in the acknowledgment section and provide the project number for all microscopes that you have used for that particular publication (you can find the project numbers in the table below):

“We would like to thank the Microscopy Core Facility of the Medical Faculty at the University of Bonn for providing support and instrumentation funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – project number xxxxxxxxx”

Microscope type	Microscope name	DFG project number
Wide-field microscope	Zeiss Observer.Z1	13123509
Slide Scanner	Zeiss Axio Scan.Z1	388168919
High-content screening microscope	Zeiss CellDiscoverer 7	388158066
Confocal microscope	Leica SP5 AOBS with SMD	169331223
Confocal microscope	Leica SP8 AOTF	266686698
Spinning Disk Microscope	VisiScope CSU-W1 with VS-Homogenizer	388169927
Confocal microscope	Leica SP8 AOBS super-resolution	388159768
Scanning electron microscope	Zeiss Crossbeam 550	388171357

 

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List of publications with MCF acknowledgements:

Kim H, Melliti N, Breithausen E, Michel K, Colomer SF, Poguzhelskaya E, Nemcova P, Ewell L, Blaess S, Becker A, Pitsch J, Dietrich D, Schoch S., 2024. Paroxysmal dystonia results from the loss of RIM4 in Purkinje cells. Brain. 2024 Mar 13:awae081. https://doi.org/10.1093/brain/awae081

Próchnicki, T., Vasconcelos, M.B., Robinson, K.S., Mangan, M.S.J., De Graaf, D., Shkarina, K., Lovotti, M., Standke, L., Kaiser, R., Stahl, R., Duthie, F.G., Rothe, M., Antonova, K., Jenster, L.-M., Lau, Z.H., Rösing, S., Mirza, N., Gottschild, C., Wachten, D., Günther, C., Kufer, T.A., Schmidt, F.I., Zhong, F.L., Latz, E., 2023. Mitochondrial damage activates the NLRP10 inflammasome. Nat Immunol 24, 595–603. https://doi.org/10.1038/s41590-023-01451-y

Antoniou, A., Auderset, L., Kaurani, L., Sebastian, E., Zeng, Y., Allahham, M., Cases-Cunillera, S., Schoch, S., Gründemann, J., Fischer, A., Schneider, A., 2023. Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF. Cell Reports 42, 112063. https://doi.org/10.1016/j.celrep.2023.112063

Dietrich, A., Steffens, U., Gajdiss, M., Boschert, A.-L., Dröge, J.K., Szekat, C., Sass, P., Malik, I.T., Bornikoel, J., Reinke, L., Maček, B., Franz-Wachtel, M., Nieselt, K., Harbig, T., Scherlach, K., Brötz-Oesterhelt, H., Hertweck, C., Sahl, H.-G., Bierbaum, G., 2022. Cervimycin-Resistant Staphylococcus aureus Strains Display Vancomycin-Intermediate Resistant Phenotypes. Microbiol Spectr 10, e02567-22. https://doi.org/10.1128/spectrum.02567-22

Arévalo, L., Merges, G.E., Schneider, S., Oben, F.E., Neumann, I.S., Schorle, H., 2022. Loss of the cleaved-protamine 2 domain leads to incomplete histone-to-protamine exchange and infertility in mice. PLoS Genet 18, e1010272. https://doi.org/10.1371/journal.pgen.1010272

Merges, G.E., Meier, J., Schneider, S., Kruse, A., Fröbius, A.C., Kirfel, G., Steger, K., Arévalo, L., Schorle, H., 2022. Loss of Prm1 leads to defective chromatin protamination, impaired PRM2 processing, reduced sperm motility and subfertility in male mice. Development 149, dev200330. https://doi.org/10.1242/dev.200330

Müller, J.A., Betzin, J., Santos-Tejedor, J., Mayer, A., Oprişoreanu, A.-M., Engholm-Keller, K., Paulußen, I., Gulakova, P., McGovern, T.D., Gschossman, L.J., Schönhense, E., Wark, J.R., Lamprecht, A., Becker, A.J., Waardenberg, A.J., Graham, M.E., Dietrich, D., Schoch, S., 2022. A presynaptic phosphosignaling hub for lasting homeostatic plasticity. Cell Reports 39, 110696. https://doi.org/10.1016/j.celrep.2022.110696

Scheiblich, H., Dansokho, C., Mercan, D., Schmidt, S.V., Bousset, L., Wischhof, L., Eikens, F., Odainic, A., Spitzer, J., Griep, A., Schwartz, S., Bano, D., Latz, E., Melki, R., Heneka, M.T., 2021. Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes. Cell 184, 5089-5106.e21. https://doi.org/10.1016/j.cell.2021.09.007

Joshi P, Riffel F, Kumar S, Villacampa N, Theil S, Parhizkar S, Haass C, Colonna M, Heneka MT, Arzberger T, Herms J, Walter J (2021). TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits. Acta Neuropathol Commun PMID: 34663480

Joshi P, Riffel F, Satoh K, Enomoto M, Qamar S, Scheiblich H, Villacampa N, Kumar S, Theil S, Parhizkar S, Haass C, Heneka MT, Fraser PE, St George-Hyslop P, Walter J (2021). Differential interaction with TREM2 modulates microglial uptake of modified Aβ species. Glia PMID: 34427354

Liao H, Winkler J, Wißfeld J, Shahraz A, Klaus C, Neumann H (2021). Low molecular weight polysialic acid prevents lipopolysaccharide-induced inflammatory dopaminergic neurodegeneration in humanized SIGLEC11 transgenic mice. Glia PMID: 34406679

Manabe T, Rácz I, Schwartz S, Oberle L, Santarelli F, Emmrich JV, Neher JJ, Heneka MT (2021). Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing. J Neurochem PMID: 34379806

Koenig PA, Das H, Liu H, Kümmerer BM, Gohr FN, Jenster LM, Schiffelers LDJ, Tesfamariam YM, Uchima M, Wuerth JD, Gatterdam K, Ruetalo N, Christensen MH, Fandrey CI, Normann S, Tödtmann JMP, Pritzl S, Hanke L, Boos J, Yuan M, Zhu X, Schmid-Burgk JL, Kato H, Schindler M, Wilson IA, Geyer M, Ludwig KU, Hällberg BM, Wu NC, Schmidt FI (2021). Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science PMID: 33436526

Kumar S, Kapadia A, Theil S, Joshi P, Riffel F, Heneka MT, Walter J (2021). Novel Phosphorylation-State Specific Antibodies Reveal Differential Deposition of Ser26 Phosphorylated Aβ Species in a Mouse Model of Alzheimer’s Disease. Front Mol Neurosci PMID: 33519377

Meyer JH, Marx J, Strack C, Holz FG, Schmitz-Valckenberg S (2020). Imaging of Therapeutic Effects of Anti-Vascular Endothelial Growth Factor Inhibitors by Optical Coherence Tomography Angiography in a Rat Model. Trans Vis Sci Tech. PMID: 32832234

Karagiannis F, Masouleh SK, Wunderling K, Surendar J, Schmitt V, Kazakov A, Michla M, Hölzel M, Thiele C, Wilhelm C (2020). Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation. Immunity PMID: 32268121

Ostendorf T, Zillinger T, Andryka K, Schlee-Guimaraes TM, Schmitz S, Marx S, Bayrak K, Linke R, Salgert S, Wegner J, Grasser T, Bauersachs S, Soltesz L, Hübner MP, Nastaly M, Coch C, Kettwig M, Roehl I, Henneke M, Hoerauf A, Barchet W, Gärtner J, Schlee M, Hartmann G, Bartok E (2020). Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2. Immunity PMID: 32294405

Kannabiran SA, Gosejacob D, Niemann B, Nikolaev VO, Pfeifer A (2020). Real-time monitoring of cAMP in brown adipocytes reveals differential compartmentation of β 1 and β 3-adrenoceptor signalling. Mol Metab.
PMID: 32247064

Klaus C, Hansen JN, Ginolhac A, Gérard D, Gnanapragassam VS, Horstkorte R, Rossdam C, Buettner FFR, Sauter T, Sinkkonen L, Neumann H, Linnartz-Gerlach B (2020). Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice. Neurobiol Aging. PMID: 32087947

Meyer JH, Larsen PP, Strack C, Harmening WM, Krohne TU, Holz FG, Schmitz-Valckenberg S (2019). Optical coherence tomography angiography (OCT-A) in an animal model of laser-induced choroidal neovascularization. Exp Eye Res. PMID: 31002822

 

List of publications with MCF authorships:

Paulussen, I., Beckert, H., Musial, T.F., Gschossmann, L.J., Wolf, J., Schmitt, M., Clasadonte, J., Mairet-Coello, G., Wolff, C., Schoch, S., Dietrich, D., 2023. SV2B defines a subpopulation of synaptic vesicles. Journal of Molecular Cell Biology mjad054. https://doi.org/10.1093/jmcb/mjad054

Kapadia, A., Theil, S., Opitz, S., Villacampa, N., Beckert, H., Schoch, S., Heneka, Michael.T., Kumar, S., Walter, J., 2023. Phosphorylation-state dependent intraneuronal sorting of Aβ differentially impairs autophagy and the endo-lysosomal system. Autophagy 1–22. https://doi.org/10.1080/15548627.2023.2252300

Thada S, Horvath GL, Müller MM, Dittrich N, Conrad ML, Sur S, Hussain A, Pelka K, Gaddam SL, Latz E, Slevogt H, Schumann RR, Burkert S (2021). Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis. Int J Mol Sci PMID: 33557133

Molitor DCA, Boor P, Buness A, Schneider RK, Teichmann LL, Körber R, Horvath GL, Koschmieder S, Gütgemann I (2021). Macrophage frequency in the bone marrow correlates with morphologic subtype of myeloproliferative neoplasm. Ann Hematol PMID: 33104881

Zhang L, Haddouti E, Beckert H, Biehl R, Pariyar S, Rüwald JM, Li X, Jaenisch M, Burger C, Wirtz DC, Kabir K, Schildberg FA (2020). Investigation of Cytotoxicity, Oxidative Stress, and Inflammatory Responses of Tantalum Nanoparticles in THP-1-Derived Macrophages. Mediators Inflamm PMID: 33343230

Bertheloot D, Naumovski AL, Langhoff P, Horvath GL, Jin T, Xiao TS, Garbi N, Agrawal S, Kolbeck R, Latz E (2016). RAGE Enhances TLR Responses through Binding and Internalization of RNA. J Immunol. PMID: 27798148

Schmid LC, Mittag M, Poll S, Steffen J, Wagner J, Geis HR, Schwarz I, Schmidt B, Schwarz MK, Remy S, Fuhrmann M (2016). Dysfunction of Somatostatin-Positive Interneurons Associated with Memory Deficits in an Alzheimer’s Disease Model. Neuron. PMID: 27641495

Meye FJ, Soiza-Reilly M, Smit T, Diana MA, Schwarz MK, Mameli M (2016). Shifted pallidal co-release of GABA and glutamate in habenula drives cocaine withdrawal and relapse. Nat Neurosci. PMID: 27348214

Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E (2016). Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Sci Transl Med. PMID: 27053774

Horvath GL, Langhoff P, Latz E (2016). Toll-Like Receptor Interactions Measured by Microscopic and Flow Cytometric FRET. Methods Mol Biol. PMID: 26803621

Labzin LI, Schmidt SV, Masters SL, Beyer M, Krebs W, Klee K, Stahl R, Lütjohann D, Schultze JL, Latz E, De Nardo D (2015). ATF3 Is a Key Regulator of Macrophage IFN Responses. J Immunol. PMID: 26416280

Hirschfeld J, Dommisch H, Skora P, Horvath G, Latz E, Hoerauf A, Waller T, Kawai T, Jepsen S, Deschner J, Bekeredjian-Ding I (2015). Neutrophil extracellular trap formation in supragingival biofilms. Int J Med Microbiol. PMID: 25959370

Pelka K, Phulphagar K, Zimmermann J, Stahl R, Schmid-Burgk JL, Schmidt T, Spille JH, Labzin LI, Agrawal S, Kandimalla ER, Casanova JL, Hornung V, Marshak-Rothstein A, Höning S, Latz E (2014). Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms. J Immunol. PMID: 25187660

Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, Espevik T, Jones B, Jarnicki AG, Hansbro PM, Busto P, Marshak-Rothstein A, Hornemann S, Aguzzi A, Kastenmüller W, Latz E (2014). The adaptor ASC has extracellular and ‘prionoid’ activities that propagate inflammation. Nat Immunol. PMID: 24952505

De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E (2014). High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nat Immunol. PMID: 24317040

Sirois CM, Jin T, Miller AL, Bertheloot D, Nakamura H, Horvath GL, Mian A, Jiang J, Schrum J, Bossaller L, Pelka K, Garbi N, Brewah Y, Tian J, Chang C, Chowdhury PS, Sims GP, Kolbeck R, Coyle AJ, Humbles AA, Xiao TS, Latz E (2013). RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J Exp Med. PMID: 24081950

Ablasser A, Schmid-Burgk JL, Hemmerling I, Horvath GL, Schmidt T, Latz E, Hornung V (2013). Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP. Nature. PMID: 24077100

Stutz A, Horvath GL, Monks BG, Latz E (2013). ASC speck formation as a readout for inflammasome activation. Methods Mol Biol. PMID: 23852599

Jin T, Perry A, Jiang J, Smith P, Curry JA, Unterholzner L, Jiang Z, Horvath G, Rathinam VA, Johnstone RW, Hornung V, Latz E, Bowie AG, Fitzgerald KA, Xiao TS (2012). Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. Immunity. PMID: 22483801