Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options. Researchers at the University Hospital Bonn (UKB) have now been able to elucidate a mechanism underlying…
Researchers at the Universities of Bonn and Singapore have discovered a new intracellular “smoke detector.” The sensor warns of damage to the mitochondria – the microscopic power plants that supply the cell with energy. If it does not function properly, chronic skin diseases can result…
There are two fundamentally different cell types in the brain, neurons and glial cells. The latter, for example, insulate the “wiring” of nerve cells or guarantee optimal working conditions for them. A new study led by the University of Bonn has now discovered another function in rodents: The results suggest that a certain type of glial cell…
Study by the University of Bonn elucidates a potential mechanism People with chronic epilepsy often experience impaired memory. Researchers at the University of Bonn have now found a mechanism in mice that could explain these deficits. The German Center for Neurodegenerative Diseases (DZNE)…
Study at the University of Bonn identifies gene that can cause malformations if altered An international study led by the medical Faculty of the University of Bonn has identified a gene that plays an important role in the development of the human embryo. If it is altered, malformations of various organ systems can result. The…
By providing technological services and expertise core facilities and their staff have a strong impact on the scientific performance and output of their host organisation.
In the absence of a high number of publications, acknowledgements are used as a measure of a core facility and its staff’s output and impact.
The acknowledgement of a core facility therefore goes beyond professional courtesy…
Study by the University of Bonn identifies new signaling pathway to combat UV damage and infections Inflammatory reactions in the skin can reduce damage from UV radiation or infections, but can also result in painful symptoms such as sunburn. A recent study at the University of Bonn and the University Hospital Bonn has now identified…
Study by the University of Bonn elucidates an important immune mechanism Hemophilia A is the most common severe form of hemophilia. It affects almost exclusively males. The disease can usually be treated well, but not for all sufferers. A study at the University of Bonn has now elucidated an important mechanism that is crucial for…
Study by the University of Bonn follows an innovative path in the search for new active substances The zebrafish serves as a model organism for researchers around the world: it can be used to study important physiological processes that also take place in a similar form in the human body. It is therefore routinely used…
Researchers at the University of Bonn discover mechanism that leads to ANCA-associated vasculitis Our own immune system can become the enemy when mechanisms that are actually protective get out of control. In ANCA-associated vasculitis, excessive inflammatory reactions lead to pulmonary hemorrhages that can be fatal if left untreated. Researchers at the University of Bonn, together…
The BONFOR Funding Instrument 9 (Technology Development in Core Facilities) is meant to ensure that the Core Facilities of the Medical Faculty can map state-of-the-art and innovative, novel methods. The innovations that are established within the framework of this project-related scientific work are then to be incorporated into the routine work of the Core Facility….
Study: Bacterial membrane transporter helps pathogens to hide from immune system The transport of substances across the membrane into the cell is linked to specific membrane transport proteins. Researchers at the University Hospital Bonn (UKB) and the University of Bonn, in collaboration with an international team, have now succeeded in elucidating the molecular structure of…