Gene scissors find target for testicular cancer therapy
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Gene scissors find target for testicular cancer therapy

Bonn researchers uncover contribution of protein degradation processes to cisplatin resistance in germ cell tumors Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options. Researchers at the University Hospital Bonn (UKB) have now been able to elucidate a mechanism underlying…

Covid-19: New energy for flagging immune cells
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Covid-19: New energy for flagging immune cells

Immune cells do not receive sufficient suitable energy carriers in infected individuals, a study reveals In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively. Perhaps this…

Immune cells in the brain share the work
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Immune cells in the brain share the work

This cooperation is impaired in mutations that can cause Parkinson’s disease To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE) and the Institut Fran├žois Jacob…