Are you excited about the possibility that your research could make a difference in the world? We’d like to help you achieve that with awards totaling EUR 60.000! All you have to do is apply and present your idea at the first ever Pitch Contest of the Medical Faculty Bonn on September 15, 2022. External…
Immune cells do not receive sufficient suitable energy carriers in infected individuals, a study reveals In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively. Perhaps this…
During sperm production, an enormous amount of DNA has to be packed into a very small space without breaking anything. A central role is played by certain proteins around which the DNA thread is wrapped – the protamines. A recent study by the University of Bonn…
The primary cilium constitutes an organelle that orchestrates signal transduction independently from the cell body. Dysregulation of this intricate molecular architecture leads to severe human diseases, commonly referred to as ciliopathies. However, the molecular underpinnings how ciliary signaling orchestrates…
Mechanism identified at University of Bonn alters the coupling of nerve cells The brain has the ability to modify the contacts between neurons. Among other things, that is how it prevents brain activity from getting out of control. Researchers from the University Hospital Bonn, together with a team from Australia, have identified a mechanism that…
Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized “mini-antibodies.” These nanobodies enabled them to dissolve molecular complexes in tissue that normally activate the immune system. The nanobodies produced may in future…
Researchers at the University of Bonn use artificial intelligence to detect rare diseases even more accurately Rare genetic diseases can sometimes be recognized through facial features, such as characteristically shaped brows, nose or cheeks. Researchers at the University of Bonn have now trained software that uses portrait photos to better diagnose such diseases. The improved…
Study of mice by the University of Bonn could enable alternative methods to animal experiments in the medium term Researchers at the University of Bonn have developed a method to generate embryo-like cell complexes from the stem cells of mice. The method provides new insights into embryonic development. In the medium term, it might also…
Dear Core Facility users and those who would like to become one, we present you our remastered handbook that will give you a short overview of techniques currently available at the Core Facilities of the Bonn Technology Campus. From now on, you will find a PDF version at the bottom of the BTC website, below…
This cooperation is impaired in mutations that can cause Parkinson’s disease To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE) and the Institut François Jacob…
Researchers at the University of Bonn investigate the role of the transcription factor for dopamine-producing neurons The neurotransmitter dopamine influences the activity of a wide variety of brain areas. A deficiency of this substance can have drastic consequences: The death of dopamine-producing nerve cells in the substantia nigra – a particularly sensitive part of the…
Study by the University of Bonn shows that mutations of the investigated gene manifest in different patterns of inheritance The so-called Plexin-A1 gene seems to play a more extensive role in brain development than previously assumed. This is shown by a current study led by the University Hospital Bonn and the Institute of Anatomy of…