Publications

Publications

Link_To_Pubmed_Entries

Selected Publications

Effects of different ratios of omega-6:omega-3 fatty acids in the diet of sows on the proteome of milk-derived extracellular vesicles. Ferreira RF, Blees T, Shakeri FBuness A, Sylvester M, Savoini G, Agazzi A, Mrljak V, Sauerwein H.J Proteomics. 2022 May 26:104632. doi: 10.1016/j.jprot.2022.104632.

Reconstruction of the origin of the first major SARS-CoV-2 outbreak in Germany. Korencak M, Sivalingam SSahu A, Dressen D, Schmidt A, Brand F, Krawitz P, Hart L, Maria Eis-Hübinger A, Buness A, Streeck H.Comput Struct Biotechnol J. 2022;20:2292-2296. doi: 10.1016/j.csbj.2022.05.011. Epub 2022 May 10.

GenRisk: A tool for comprehensive genetic risk modeling. Aldisi R, Hassanin E, Sivalingam S, Buness A, Klinkhammer H, Mayr A, Fröhlich H, Krawitz P, Maj C. Bioinformatics. 2022 Mar 10:btac152. doi: 10.1093/bioinformatics/btac152.

GestaltMatcher facilitates rare disease matching using facial phenotype descriptors. Hsieh TC, Bar-Haim A, Moosa S, Ehmke N, Gripp KW, Pantel JT, Danyel M, Mensah MA, Horn D, Rosnev S, Fleischer N, Bonini G, Hustinx A, Schmid A, Knaus A, Javanmardi B, Klinkhammer H, Lesmann H, Sivalingam S, Kamphans T, Meiswinkel W, Ebstein F, Krüger E, Küry S, Bézieau S, Schmidt A, Peters S, Engels H, Mangold E, Kreiß M, Cremer K, Perne C, Betz RC, Bender T, Grundmann-Hauser K, Haack TB, Wagner M, Brunet T, Bentzen HB, Averdunk L, Coetzer KC, Lyon GJ, Spielmann M, Schaaf CP, Mundlos S, Nöthen MM, Krawitz PM. Nat Genet. 2022 Mar;54(3):349-357. doi: 10.1038/s41588-021-01010-x. Epub 2022 Feb 10.

Overexpression of Parkin in clear cell renal cell carcinoma decreases tumor aggressiveness by regulating CKS2 levels. Esser LK, Branchi V, Shakeri F, Simon AG, Stephan C, Kristiansen G, Buness A, Schorle H, Toma MI. Int J Oncol. 2022 Feb;60(2):20. doi: 10.3892/ijo.2022.5310. Epub 2022 Jan 21.

Iron Deficiency Caused by Intestinal Iron Loss-Novel Candidate Genes for Severe Anemia. Huettmann C, Stelljes M, Sivalingam S, Fobker M, Vrachimis A, Exler A, Wenning C, Wempe C, Penke M, Buness A, Ludwig KU, Muckenthaler MU, Steinbicker AU. Genes (Basel). 2021 Nov 24;12(12):1869. doi: 10.3390/genes12121869.

Variant profiling of colorectal adenomas from three patients of two families with MSH3-related adenomatous polyposis. Perne C, Peters S, Cartolano M, Horpaopan S, Grimm C, Altmüller J, Sommer AK, Hillmer AM, Thiele H, Odenthal M, Möslein G, Adam R, Sivalingam S, Kirfel J, Schweiger MR, Peifer M, Spier I, Aretz S. PLoS One. 2021 Nov 29;16(11):e0259185. doi: 10.1371/journal.pone.0259185. eCollection 2021.

Genome-Wide Survey for Microdeletions or -Duplications in 155 Patients with Lower Urinary Tract Obstructions (LUTO). Schierbaum LM, Schneider S, Herms S, Sivalingam S, Fabian J, Reutter H, Weber S, Merz WM, Tkaczyk M, Miklaszewska M, Sikora P, Szmigielska A, Krzemien G, Zachwieja K, Szczepanska M, Taranta-Janusz K, Kroll P, Polok M, Zaniew M, Hilger AC. Genes (Basel). 2021 Sep 20;12(9):1449. doi: 10.3390/genes12091449.

Machine learning to guide clinical decision-making in abdominal surgery-a systematic literature review. Henn J, Buness A, Schmid M, Kalff JC, Matthaei H. Langenbecks Arch Surg. 2021 Oct 29. doi: 10.1007/s00423-021-02348-w.

Comparative proteome profiling in exosomes derived from porcine colostrum versus mature milk reveals distinct functional proteomes. Ferreira RF, Blees T, Shakeri F, Buness A, Sylvester M, Savoini G, Agazzi A, Mrljak V, Sauerwein H.J Proteomics. 2021 Jul 31:104338. doi: 10.1016/j.jprot.2021.104338.

TBK1 and TNFRSF13B mutations and an autoinflammatory disease in a child with lethal COVID-19. Schmidt A, Peters S, Knaus A, Sabir H, Hamsen F, Maj C, Fazaal J, Sivalingam S, Savchenko O, Mantri A, Holzinger D, Neudorf U, Müller A, Ludwig KU, Krawitz PM, Engels H, Nöthen MM, Bagci S.NP J Genom Med. 2021 Jul 1;6(1):55. doi: 10.1038/s41525-021-00220-w.

Extending the allelic spectrum at noncoding risk loci of orofacial clefting. Thieme F, Henschel L, Hammond NL, Ishorst N, Hausen J, Adamson AD, Biedermann A, Bowes J, Zieger HK, Maj C, Kruse T, Buness A, Hoischen A, Gilissen C, Kreusch T, Jäger A, Gölz L, Braumann B, Aldhorae K, Rojas-Martinez A, Krawitz PM, Mangold E, Dixon MJ, Ludwig KU. Hum Mutat. 2021 May 18. doi: 10.1002/humu.24219.

Differential proteome between ejaculate and epididymal sperm represents a key factor for sperm freezability in wild small ruminants. Martínez-Fresneda L, Sylvester M, Shakeri F, Bunes A, Del Pozo JC, García-Vázquez FA, Neuhoff C, Tesfaye D, Schellander K, Santiago-Moreno J. Cryobiology. 2021 Apr;99:64-77. doi: 10.1016/j.cryobiol.2021.01.012.

Prognostic Gene Expression, Stemness and Immune Microenvironment in Pediatric Tumors. Stahl D, Knoll R, Gentles AJ, Vokuhl C, Buness A, Gütgemann I. Cancers (Basel). 2021 Feb 18;13(4):854. doi: 10.3390/cancers13040854.

Macrophage frequency in the bone marrow correlates with morphologic subtype of myeloproliferative neoplasm. Molitor DCA, Boor P, Buness A, Schneider RK, Teichmann LL, Körber RM, Horvath GL, Koschmieder S, Gütgemann I. Ann Hematol. 2021 Jan;100(1):97-104. doi: 10.1007/s00277-020-04304-y.

High-Dimensional Analysis of Immune Cell Composition Predicts Periprosthetic Joint Infections and Dissects Its Pathophysiology. Korn MF, Stein RR, Dolf A, Shakeri F, Buness A, Hilgers C, Masson W, Gravius S, Kohlhof H, Burger C, Wirtz DC, Randau TM, Schildberg FA. Biomedicines. 2020 Sep 17;8(9):358. doi: 10.3390/biomedicines8090358.

Protamine-2 Deficiency Initiates a Reactive Oxygen Species (ROS)-Mediated Destruction Cascade during Epididymal Sperm Maturation in Mice. Schneider S, Shakeri F, Trötschel C, Arévalo L, Kruse A, Buness A, Poetsch A, Steger K, Schorle H. Cells. 2020 Jul 27;9(8):1789. doi: 10.3390/cells9081789.

Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome. Wang H, Humbatova A, Liu Y, Qin W, Lee M, Cesarato N, Kortüm F, Kumar S, Romano MT, Dai S, Mo R, Sivalingam S, Motameny S, Wu Y, Wang X, Niu X, Geng S, Bornholdt D, Kroisel PM, Tadini G, Walter SD, Hauck F, Girisha KM, Calza AM, Bottani A, Altmüller J, Buness A, Yang S, Sun X, Ma L, Kutsche K, Grzeschik KH, Betz RC, Lin Z. Am J Hum Genet. 2020 Jul 2;107(1):34-45. doi: 10.1016/j.ajhg.2020.05.006. Epub 2020 Jun 3.

A high-salt diet compromises antibacterial neutrophil responses through hormonal perturbation. Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C. Sci Transl Med. 2020 Mar 25;12(536):eaay3850. doi: 10.1126/scitranslmed.aay3850.

Altered Notch Signaling in Dowling-Degos Disease: Additional Mutations in POGLUT1 and Further Insights into Disease Pathogenesis. Ralser DJ, Takeuchi H, Fritz G, Basmanav FB, Effern M, Sivalingam S, El-Shabrawi-Caelen L, Degirmentepe EN, Kocatürk E, Singh M, Booken N, Spierings NMK, Schnabel V, Heineke A, Knuever J, Wolf S, Wehner M, Tronnier M, Leverkus M, Tantcheva-Poór I, Wenzel J, Oji V, Has C, Hölzel M, Frank J, Haltiwanger RS, Betz RC. J Invest Dermatol. 2019 Apr;139(4):960-964. doi: 10.1016/j.jid.2018.10.030. Epub 2018 Nov 9.