Enzyme prevents brain activity from getting out of control
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Enzyme prevents brain activity from getting out of control

Mechanism identified at University of Bonn alters the coupling of nerve cells The brain has the ability to modify the contacts between neurons. Among other things, that is how it prevents brain activity from getting out of control. Researchers from the University Hospital Bonn, together with a team from Australia, have identified a mechanism that…

New approach against chronic inflammation
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New approach against chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized “mini-antibodies.” These nanobodies enabled them to dissolve molecular complexes in tissue that normally activate the immune system. The nanobodies produced may in future…

Facial analysis improves diagnosis
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Facial analysis improves diagnosis

Researchers at the University of Bonn use artificial intelligence to detect rare diseases even more accurately Rare genetic diseases can sometimes be recognized through facial features, such as characteristically shaped brows, nose or cheeks. Researchers at the University of Bonn have now trained software that uses portrait photos to better diagnose such diseases. The improved…

Stem cells organize themselves into embryoid
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Stem cells organize themselves into embryoid

Study of mice by the University of Bonn could enable alternative methods to animal experiments in the medium term Researchers at the University of Bonn have developed a method to generate embryo-like cell complexes from the stem cells of mice. The method provides new insights into embryonic development. In the medium term, it might also…

Article in “Forschung&Lehre” about Core Facilities

Article in “Forschung&Lehre” about Core Facilities

as you can already see from our Handbook, there are two questions we get asked frequently: What is a Core Facilitity and what is it good for? By coincidence, the Journal “Forschung&Lehre” asked themselves in the October issue of their journal, how “Forschungswerkzeuge” or Research Infrastructures support science. We provided them an article on how…

Immune cells in the brain share the work
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Immune cells in the brain share the work

This cooperation is impaired in mutations that can cause Parkinson’s disease To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE) and the Institut Fran├žois Jacob…

BCL11A: Evidence for neuroprotective effect
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BCL11A: Evidence for neuroprotective effect

Researchers at the University of Bonn investigate the role of the transcription factor for dopamine-producing neurons The neurotransmitter dopamine influences the activity of a wide variety of brain areas. A deficiency of this substance can have drastic consequences: The death of dopamine-producing nerve cells in the substantia nigra – a particularly sensitive part of the…

Gene plays major role in brain development
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Gene plays major role in brain development

Study by the University of Bonn shows that mutations of the investigated gene manifest in different patterns of inheritance The so-called Plexin-A1 gene seems to play a more extensive role in brain development than previously assumed. This is shown by a current study led by the University Hospital Bonn and the Institute of Anatomy of…

Molecule attacks coronavirus in a novel way
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Molecule attacks coronavirus in a novel way

Active ingredient inhibits infection with so-called pseudoviruses in the test tube, as shown by study at the University of Bonn Scientists at the University of Bonn and the caesar research center have isolated a molecule that might open new avenues in the fight against SARS coronavirus 2. The active ingredient binds to the spike protein…

New promising antibodies against SARS-CoV-2
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New promising antibodies against SARS-CoV-2

Study in Science: Combination of two molecules simultaneously attacks multiple sites on the surface of the virus An international research team led by the University of Bonn has identified and further developed novel antibody fragments against the SARS coronavirus-2. These “nanobodies” are much smaller than the classic antibodies used to treat US President Donald Trump,…