You want to establish a new mouse model with us? Please contact us via gene.editing@uni-bonn.de to arrange a first meeting where we can discuss your project ideas and figure out the method of choice for your needs. Of course, advice is provided free of charge.
If you decide on establishing your mouse model with us, we will develop a gene-editing strategy in close collaboration with you. To assign us to generate your mouse model, please fill out the order form and send it back to us via fax or email. In addition you have to fill out an advice of amendment, which we will submit to the local authority to receive the permission to generate the requested mouse line. Usually the permission is granted within 4-5 weeks. Once the constructs are ready and the permission is granted, we will perform the zygotes manipulations. Developing embryos will be transferred into pseudopregnant foster mice. After weaning of offspring you will receive genomic material to perform the genotyping and hopefully identify gene-editing positive founder animals. If you wish, we are happy to help you setting up a genotyping protocol. Founder animals can then be transferred to your animal facility for further breeding.
