At the TGS scientists and expert technicians will help you to generate and establish genetically modified mice using different state-of-the-art techniques. Visit the core facility and discuss alternative strategies to approach the realization of your specific ideas in connection of new genetic in-vitro and in vivo models.
The TGS currently establishes the service of knock-in mouse generation via the CRISPR/Cas-mediated genome editing approach. Applications of the state-of-art techniques customized types of gene modification according to investigators‘ needs (illustrated in Figure 1).
Adapted from Yang al. Nature Protocols