Instrumentation

Thermo Orbitrap Tribrid Fusion Lumos

Lumos

ThermoScientific Orbitrap Fusion Lumos

The „Lumos“ is our flagship: A state-of-the-art hybrid instrument that has a quadrupole, Orbitrap, and ion-trap mass analyzer. In combination with three different fragmentation methods (including electron transfer dissociation – ETD) it is one of the most versatile instruments available. All high throughput projects will benefit from its sensitivity and speed. Modern measurement modes are available: analyses of intact proteoforms, data-independent (DIA) and targeted techniques (PRM).

 

 

Thermo Orbitrap Velos

Velos

ThermoScientific Orbitrap Velos

The Orbitrap Velos has two detectors: a fast low resolution linear ion trap and a high resolution, high accuracy Orbitrap detector which can be used in parallel. This instrument is a workhorse for proteome analyses and whenever high resolution is needed.

 

 

MALDI-TOF/TOF Bruker Autoflex III

MALDI

Bruker Autoflex III MALDI-TOF

Our MALDI-TOF instrument is a versatile tool for fast analyses of proteins and peptides. Low complexity protein samples such as from 2D gel spots can be analyzed with good mass accuracy and resolution. The TOF detector can also be used for intact protein mass measurements and fast characterization of protein preparations.

 

 

nanoLC systems

lcsagilentThree ultra-high performance liquid chromatographs for nanoflow (~300 nl/min) are used for coupling with mass spectrometers. These systems perform chromatographic separations very reproducibly and assure a stable delivery of analytes to the mass spectrometers. Columns are made in-house. 
A variety of sample preparation devices can be used to handle larger sets of samples. If necessary protein complexity is reduced by various fractionation methods.

Advion Triversa Nanomate

A Nanomate nanospray robot can be used for automated delivery of small sample amounts for direct infusion.